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Dataset from Zenodo · Tcheremenskaia, Olga

Update of the EFSA Pesticide Genotoxicity Database

Open on Zenodo
License
CC BY 4.0commercial use allowedLicense text
This license allows commercial use. Usually you must credit the author; read the license for the exact terms.
Formats
ZIP, XLSX
Size
106 MB
Updated
Jun 3, 2026

Description

Genotoxicity is one of the most important endpoints for human health. Several large databases of genotoxicity results are available for training the predictive systems. This has given rise to the generation of a large number of (Q)SAR models and Read-Across approaches. The main objectives of the contract OC/EFSA/SCER/2021/05 and its follow-up contract PO/EFSA/PREV/2025/02 were to update the existing EFSA genotoxicity database developed under the previous Contract GP/EFSA/PRAS/2014/01 through IUCLID application as well to migrate the existing data to IUCLID format. Chemical and genotoxicity information for pesticides active substances and their metabolites has been extracted from the EFSA draft/renewals assessment reports and entered into IUCLID according to the operational procedures developed under the project. In total, considering all IUCLID entries, the update includes 143 active substances and 279 metabolites. The final database available in both Excel and IUCLID formats includes 389 active substances, 1058 metabolites, 6119 genotoxicity studies (26198 data points). In addition, under the new contract PO/EFSA/PREV/2025/02, 87 substances were added to this final database, in…

Description from Zenodo, shortened.

Files (4)

  • ZIPOC_EFSA_SCER_2021_05.zip66 MB
  • ZIPPO_EFSA_PREV_2025_02.zip23 MB
  • XLSXOC_EFSA_SCER_2021_05.xlsx15 MB
  • XLSXPO_EFSA_PREV_2025_02.xlsx2.3 MB

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